Programmed DNA Elimination

Launay C, Wenger E, Letcher B, Delattre M. Somatic Programmed DNA Elimination is widespread in free-living Rhabditidae nematodes 2025. biorXiv. doi:10.1101/2025.08.21.671558Under review - eLife

Sex chromosome evolution & genetic conflicts

Letcher B, Stevens L, Saclier N, Hsiao A, Kieninger M, Wenger E, et al. Emergence and stabilisation of a neo-Y chromosome in nematode species with rare males. bioRxiv; 2026 doi:10.1101/2025.07.25.666552Under revision - MBE

Pathogen genomics & evolution

Letcher B, Maciuca S, Iqbal Z. Role for gene conversion in the evolution of cell-surface antigens of the malaria parasite Plasmodium falciparum. PLOS Biology. 2024 Mar 7;22(3):e3002507. doi:10.1371/journal.pbio.3002507

Walker TM, Miotto P, Köser CU, Fowler PW, Knaggs J, Iqbal Z, et al. The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis. The Lancet Microbe. 2022 Mar 8;0(0). doi:10.1016/S2666-5247(21)00301-3

Bioinformatics - Tools

Letcher B, Delattre M. delfies: a Python package for the detection of DNA breakpoints with neo-telomere addition. Journal of Open Source Software. 2025 Jan 12;10(105):7385. doi:10.21105/joss.07385Programmed DNA Elimination

Letcher B, Hunt M, Iqbal Z. Gramtools enables multiscale variation analysis with genome graphs. Genome Biol. 2021 Dec;22(1):259. doi:10.1186/s13059-021-02474-0Pathogen genomics

Hunt M, Letcher B, Malone KM, Nguyen G, Hall MB, Colquhoun RM, et al. Minos: variant adjudication and joint genotyping of cohorts of bacterial genomes. Genome Biology. 2022 Jul 5;23(1):147. doi:10.1186/s13059-022-02714-xPathogen genomics

Mölder F, Jablonski KP, Letcher B, Hall MB, Tomkins-Tinch CH, Sochat V, et al. Sustainable data analysis with Snakemake. F1000Research; 2021. doi:10.12688/f1000research.29032.2Workflow management